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This blogs provides information, trainning and news of the Granulation technology used at the Pharmaceutical Industry. In this way this blogs could be used at source of information for the Pharmacist and Pharmaceutical students, Master or PhD who want to be informed in this interesting themes

sábado, 10 de enero de 2009

Nanoparticle: Drug delivery system for cancer therapy

Nanoparticle: Drug delivery system for cancer therapyNisha Mary Joseph1, Pramod Kumar Sharma21 School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia2 Institute of Bundelkhand University, Jhansi, Uttar Pradesh, India


Nanoparticle has emerged as a promising strategy for the efficient delivery of drugs used in the treatment of cancer by avoiding the reticuloendothelial system, utilizing the enhanced permeability and retention effect and tumor-specific targeting. Delivery methods using nanoparticle are highlighted including both degradable and non-degradable polymers. The preparation techniques include emulsion polymerization, micelle polymerization, desolvation of macromolecule, and emulsion-solvent evaporation methods. The particle size of the polymeric nanoparticle is in the nanometer range (10-1000 nm) and is dependent on the method of preparation employed.

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